Islamabad is 4 hours ahead of Milan
Best overlap: 8:00 AM to 2:00 PM in Milan is 12:00 PM to 6:00 PM in Islamabad.
Target 8:00 AM to 2:00 PM in Milan, which lands at 12:00 PM to 6:00 PM for the Islamabad side. The overlap is wide at 6 hours, so you can protect mornings for deep work and still find plenty of meeting time. Daylight saving complicates things slightly: Milan observes it, Islamabad doesn't, so the difference flexes by an hour part of the year.