Prague is 6 hours ahead of Medellín
Best overlap: 8:00 AM to 12:00 PM in Medellín is 2:00 PM to 6:00 PM in Prague.
Medellín and Prague overlap from 8:00 AM to 12:00 PM (Medellín) to the equivalent 2:00 PM to 6:00 PM in Prague — that's your meeting window. The overlap sits at about 4 hours; aim for the heart of it so the call isn't too early for one team or too late for the other. A quick caveat — Prague's clocks move for daylight saving and Medellín's don't, so the times here are right for only part of the year.