Anchorage is 14 hours behind Karachi
There is no standard 8-to-6 overlap. Someone joins early or late.
The 14-hour difference means Karachi and Anchorage miss each other entirely during regular office hours. Where you can, lean on async updates and save live calls for when one team is happy to start early or stay late. Seasonal note: Anchorage uses daylight saving and Karachi doesn't, so double-check the times in your own months — they can move by an hour.