Karachi is 8 hours ahead of Brasília
Best overlap: 8:00 AM to 10:00 AM in Brasília is 4:00 PM to 6:00 PM in Karachi.
Both teams are at their desks between 8:00 AM to 10:00 AM in Brasília and 4:00 PM to 6:00 PM in Karachi. You've got roughly 2 hours — enough for a focused daily check-in if you hold it at 8:00 AM in Brasília (4:00 PM in Karachi).